“The importance of sharing clinical information: the case report of an adverse reaction” was written by Alexandra Cadete, Lara Sutil, Carine Silva and Joana Simões. Below, what I learned reading this text.
- A doctor may employ a treatment even when there is no consensus on the safety and effectiveness of its use (not that it’s always a good thing)…
- When applying antiemetic therapy, it is necessary to choose well which medicine to use, since the incidence of adverse reactions can reach 25% if the subject undergoing therapy is a child.
- The extrapyramidal effect, which may be caused by metoclopramide, may be reversed with biperiden.
- Metoclopramide can cause a dystonic crisis even without overdose.
- If a child is vomiting and an antiemetic must be used, ondansetron or domperidone are better choices, but not metoclopramide.
- Antiemetic therapy is used when a vomiting crisis begins to cause dehydration.
- A dystonic crisis can occur up to two days after metoclopramide use.
- Such reactions are characterized by abnormal postures, spasms and twisting movements.
- This effect is more common in children and the elderly, but rare in young adults.
- If these effects appear without the subject taking antidopaminergic medication, the patient may have tetanus or a disorder that causes seizure.
- An extrapyramidal reaction may be reversed with anticholinergics or benzodiazepines.